Drugstore: the science of the design of the pharmaceutical forms
· Author: Aulton, M.E. · ISBN: 84-8174-728-9
The second edition of a text of world success, which first edition published in 1988 has been used like text, of way continued from this date, in many Departments of pharmaceutics of the whole world. The target of this work is to provide to the pharmacists the necessary knowledge to turn a potential drug into a medicine that could be administered to the patient of a sure and efficient way. It treats as an exhaustive way the Science of the design of the pharmaceutical forms and all the ways of presentation of the medicines. In his wide sense this work is an ôCiencia of the boticaö or of the pharmaceutical preparations, therefore it is a fundamental matter inside the university curriculum and inside the pharmacist's profession. It includes the design and medicines formulation, for what there are taught the necessary aspects of physical chemistry, his production to small scale (composed) and large-scale (pharmaceutical technology) and the elimination of microorganisms of the medicines. Although the basic sciences remain practically invariable, there are other fields like the biodrugstore, some aspects of the administration of medicines, the properties of the solid state and products of biotechnology that yes have changed, for what there was becoming indispensable a new edition of this successful text, which teachers and pupils have been claiming during the last years. This new edition is structured in five parts: 1) Scientific Beginning of the design of the pharmaceutical forms; 2) Science of the particles and technology related to the dust; 3) biopharmaceutical Beginning of the administration of medicines; 4) Design and manufacture of the pharmaceutical forms; 5) Pharmaceutical microbiology; along that there are covered completely the contents of the subjects of Galénica and Pharmaceutical technology, for what this work is the resource most recognized and spread for the study of these matters.
INDEX: The design of the pharmaceutical forms. I. Scientific beginning of the design of the pharmaceutical forms. Dissolution and solubility. Properties of the solutions. Rheology. Superficial phenomena and of interface. Dispersed systems. Kinetics and stability of the product. Pharmaceutical preformulation. II. Science of the particles and technology related to the dust. Properties of the solid state. Analysis of the size of the particles. Reduction of the size of the particles. Separation for the size of the particles. Mixed. Dust flow. III. Biopharmaceutical beginning of the administration of medicines. Introduction to the biodrugstore. The digestive tract: physiology and pharmacological absorption. Bioavailability: factors fisicoquímicos and of the pharmaceutical form. Evaluation of the biopharmaceutical properties. Systems posológicos. Stuart Proudfoot, (updated by John Collett). Oral pharmaceutical form of modified liberation. III. Biopharmaceutical beginning of the administration of medicines. Introduction to the biodrugstore. The digestive tract: physiology and pharmacological absorption. Bioavailability: factors fisicoquímicos and of the pharmaceutical form. Evaluation of the biopharmaceutical properties. Systems posológicos. Stuart Proudfoot, (updated by John Collett). Oral pharmaceutical form of modified liberation. IV. Design and manufacture of the pharmaceutical forms. Solutions. Aclaramiento. Suspensions and emulsions. Dust and granules. Granulation. Drying. Tablets and compression. Recovering of tablets and multiparticles. Capsules of hard gelatine. Capsules of soft gelatine. Administration of medicines for pulmonary route. Administration of medicines for nasal route. Administration of medicines for route transdérmica. Administration of medicines for rectal and vaginal route. Administration of pharmaceutical proteins. Packings and packed. Design of a pharmaceutical plant. Heat transfer and properties and steam employment...
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